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Evidence for epigenetic regulation of gene expression and function in chronic experimental diabetic neuropathy

Mayo Clinic 2017)

FOXOs control a plethora of cellular functions, such as cell growth, survival, metabolism and oxidative stress, by regulating the expression of several targeted genes The next question is why FOXO4, versus any other number: inhibition of FOXO4 expression using a lentiviral shRNA made cells undergo apoptosis rather than become senescent upon irradiation

With the increasing number of individuals infected and re-infected across the world, microglia may have a role in the pathophysiology of post-COVID-19 neurological diseases, including PD [65]