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Calculations are shown for both the 5 days/week and 3 times/week schedules

In males, potential causes for infertility include low or no sperm count, poor sperm motility, and sexual or ejaculatory dysfunction

reported Phase I study results in healthy volunteers demonstrating favorable safety and clear dose-dependent pharmacodynamic characteristics under both single and multiple dosing conditions ( 6.1.1.2 Japanese population studies Another Phase I study in healthy Japanese and Caucasian volunteers further confirmed brensocatibs pharmacokinetic characteristics