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SURMOUNT-MAINTAIN (Horn 2026, 112 weeks): continued top dose -21.9% vs 5 mg step-down -16.6% vs placebo -9.9%, rescue therapy 8/25/67%: Aronne JAMA 2024

But a huge number of meat eaters are also deficient and likely dont know it B12 is absorbed through the stomach, and our ability to assimilate it through the stomach wall decreases with age, as well as due to any stomach issues like IBS, Crohns, and Celiac Disease, and medications that impact the stomach like metformin, antacids, PPIs, and ibuprofen

M., & Belykh, A