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Moreover, fragmented DNA may impair the paternal genetic ability to develop embryos ( Advanced proteomic tools allow the characterization of semen profiles by applying mechanistic approaches and are helpful for detecting proteins and their underlying molecular mechanisms, which can predict the significance of male fertility-related hindrances ( Male infertility cases can be diagnosed through the evaluation of basic semen characteristics, such as liquefaction time, sperm count, motility, morphological features, and sperm viability