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Modulating mitochondrial quality control Mitophagy inducers By activating the AMPK, metformin instigates a signaling cascade that culminates in the phosphorylation of ULK1, thereby facilitating mitophagy [26]

doi: 10.1016/0016-5085(93)91022-a

doi: 10.3389/fonc.2025.1524182 Received 07 November 2024 Accepted 03 February 2025 Published 20 February 2025 Volume 15 - 2025 Edited by Defang Li, Binzhou Medical University, China Reviewed by Manuel Valenzuela-Valderrama, Central University of Chile, Chile Ruo Wang, Shanghai Jiao Tong University, China Updates Copyright 2025 Zhou, Wu, Gu, Yang, Tu and Huang

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