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Mutants for phyA showed increased resistance to BSO as well as to arsenic (Sung et al., 2007), and ars5 had enhanced levels of glutathione when exposed to arsenic, accompanied by increased GSH1 and GSH2 transcripts (Sung et al., 2009)

doi: 10.1097/SCS.0000000000000783

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The interaction of these species with specific vascular or interstitial components yield potent chemoattractants for inflammatory phagocytes, establishing a self-amplifying cycle of ROS production that may overwhelm defense strategies resulting in tissue damage (Lewis et al, 1988