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Various stressorsincluding nociception-induced stress, chronic stress, and restraint stresshave been shown to cause melanocyte stem cell loss and hair graying through immunological mechanisms, corticosterone, and norepinephrine.22,23 Melanocyte stem cells express 2-adrenergic receptors, which respond to norepinephrine

BRACKET METHOD Bracket Position 1 Place the TAN patch two finger widths to the left of the pain and place the WHITE patch two finger widths to the right of the pain

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