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Consent for publication All the authors read and approved the final version of the manuscript

He had a keen interest as was recently needing B12 injections himself and not coping on the NHS regime

Investigators are particularly interested in determining the mechanisms by which effects observed in murine models relate to broader mammalian metabolic regulation, and whether different experimental conditions (young vs aged models, healthy vs metabolically compromised states) show differential responses to NNMT inhibition