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It was observed that the treatment of rats on a high-fat diet with exendin-4 resulted in a decrease in the number of osteoclasts and the area of eroded surfaces, while there was an increase in the osteoid area, bone mass, and trabecular bone volume

Although many studies with glutathione have not shown serious adverse reactions, mild side effects have been documented with glutathione taken orally including: Because supplements such as glutathione are not regulated as rigorously as drugs by the FDA, the quality of products sold as supplements can be difficult to verify

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