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According to Rita Balice-Gordon, CEO of Muna Therapeutics, small molecules that work differently than antibodies might be a better bet

In: Proceedings of the ASME summer bioengineering conference Clark ER (1918) Studies on the growth of blood-vessels in the tail of the frog larvaby observation and experiment on the living animal

Additional risk factors include: Chronic kidney disease : Reduced renal clearance may impair B12 excretion Liver disease : Hepatic dysfunction can disrupt B12 metabolism and storage Myeloproliferative disorders : Certain blood cancers increase B12-binding proteins Concurrent medication use : Some drugs may interact with B12 metabolism, including metformin, proton pump inhibitors, and H2 antagonists Patients with these conditions should have B12 supplementation carefully monitored by their healthcare team