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The link between nicotine addiction and other substance use disorders is that nicotine addiction serves as a gateway to other substance use disorders, as individuals who are addicted to nicotine incur a higher susceptibility to alcohol and drug use

People who ingest nicotine may take around 525 minutes longer than nonsmokers to fall asleep

Furthermore, tobacco smoking profoundly altered oral microbial composition, enriching Bifidobacterium , Lactobacillus , and the phylum Actinobacteria while depleting Proteobacteria, with notable taxa-level changes

A perfect recipe for disaster: cigarettes, one of the most harmful things there is for human health, is a vehicle for nicotine, whose addictive effects make people, at a certain point, smoke more and more, unable to stop