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The specific amount of weight you might lose from Zepbound is uncertain, but significant weight loss ranging from 35.5 lb (16.1 kg) to 52.0 lb (23.6 kg) was observed in the 72-week SURMOUNT-1 clinical trial, which compared different Zepbound (tirzepatide) doses to a placebo (inactive treatment)

A waiver authority exists under the legislation, but Sims indicated it would not be widely used

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The medication reaches high concentrations in skin tissue, making it particularly effective against the localized infection that develops at the bite site before spreading throughout the body