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AT Aaron T

Biomater., 9(2), E33 (2018)

This nonapeptide, first isolated from the cerebral venous blood of rabbits during sleep, has been shown to induce slow-wave sleep, modulate pain perception, and exhibit potential antioxidant and immunomodulatory properties

This mechanism concurrently suppresses skeletal muscle atrophy with secondary fibrosis and facilitates mutant SOD1 aggregate clearance, ultimately delaying disease progression and extending survival in ALS animal models (Wen et al., 2021)