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Neurochem Int 56:611619 Karunakaran D, Diwakar L, Saeed U, Agarwal V, Ramikrishnan S, Iyengar S et al (2007) Activation of apoptosis signal regulating kinase 1 (ASK1) and translocation of death-associated protein, Daxx, in substantia nigra pars compacta in a mouse model of Parkinsons disease: protection by alpha lipoic acid

This previous study also revealed that this phosphorylation is driven by E2 and is not inhibited by estrogen receptor antagonists (104), suggesting a potential alteration in AKT signaling in endometriosis, making it more responsive to estrogen or resistant to conventional antagonism

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