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This migration is mediated through the FAK-paxillin pathway, a signaling cascade that controls how cells move and attach to surrounding tissue

Endocrine Biomarkers: Utilized in controlled models measuring endocrine-linked metabolic readouts alongside pathway markers

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Because of its structural differences, IGF-1 LR3 shows reduced affinity for certain IGF-binding proteins (IGFBPs) in vitro, enabling researchers to study more sustained receptor engagement and downstream signaling under controlled conditions