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NAC serves as a precursor of cysteine and stimulates the synthesis of glutathione in neural cells

The other pharmacological approaches for targeting 7nAChR include drugs promising to have therapeutic effects through 7nAChR, which are not essential to be agonists

Qian M, Cheng Z, Luo G, Galluzzi M, Shen Y, Li Z, et al

For the dietary intervention studies (Table 2, n = 6 publications representing 5 independent trials), data extraction included study design and quality indicators, sample characteristics and diagnostic criteria, details of the intervention such as diet type, duration, and adherence monitoring, outcome measures including opioid peptide levels and behavioral assessments, and reported results along with effect sizes