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Despite the high drug loading capacity, or relatively easy modification with various ligands, this type of nanocarriers has been rarely investigated at the targeted brain drug delivery research field [50]

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Chronic high sugar levels have been associated with low glutathione levels

Intriguingly, a competitive relationship between the homologues CHAC1 and CHAC2 was observed in human embryonic stem cells (hESCs), where they play opposing roles in maintaining cellular GSH levels and regulating differentiation (Wang et al., 2017)