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Method development and validation

Babizhayev MA1996Failure to withstand oxidative stress induced by phospholipid hydroperoxides as a possible cause of the lens opacities in systemic diseases and ageing.Biochim Biophys Acta.131528799

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Caspase-Glo 1 Inflammasome Assay detects caspase-1 activity Specific to inflammasome-mediated signaling Connects immune signaling to cell death pathways Moving into 3D culture systems or combining multiple readouts in a single well introduces new experimental considerations, and the assay approach matters for both