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MMPs are enzymes that increase in response to oxidative stress and inflammation, accelerating collagen breakdown and contributing to premature aging

One study concluded that B5 supplementation was able to reduce area-specific and inflammatory lesions on the skin

A clinical trial involving sulforaphane supplements noted side effects of flatulence, constipation, and diarrhea.[ref] The clinical trials using sulforaphane can be a bit confusing because some list the amount of sulforaphane and others list broccoli extract amount, which contains more than just sulforaphane