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Concomitantly with the development of resistance the up-regulation of a hydrogen-peroxide inducible GST was observed that might contribute to the elimination of cytotoxic reactive metabolites containing an electrophilic moiety (Shibu et al., T

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Hematopoietic stem cells (HSC) circulate under steady state conditions in peripheral blood to i) to maintain a stem cell pool in remote bone marrow locations in the body and ii) to patrol peripheral tissues and organs and, when needed, to respond to organ injuries and infections

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