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Dependency of AML LSCs on mitochondrial function is associated with decreased levels of mitochondrial reactive oxygen species and concomitantly increased reliance on OxPhos rather than glycolysis as in normal HSCs to meet the cells energy demand (25)

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Abstract The resurgence of research into cancer metabolism has recently broadened interests beyond glucose and the Warburg effect to other nutrients, including glutamine

Stimulation of TNF receptor type 2 expands regulatory T cells and ameliorates established collagen-induced arthritis in mice