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When caloric restriction is present, mammals synthesise less IGF-1 and its synthesis in the liver is refractory to GH stimulation [128130]

10.1186/s10020-024-00873-0 294 LuL.LiW.SunC.KangS.LiJ.LuoX.et al

167 Drugs that stimulate these receptors, known as melatonin receptor agonists, mimic melatonin by binding to and activating the same receptors, inducing sleep

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