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3) and its long-term effects (beyond 4 weeks) on cardiac function after MI are still being explored, and further studies are needed to assess their therapeutic potential in humans after MI or ischemic insults in other organs

L.MarikawaY

Ferroptotic agents induce endoplasmic reticulum stress to promote PUMA expression through the PERK-eIF2-ATF4-CHOP pathway (73), but this form of PUMA does not lead to cell apoptosis